Administration of 2% chlorhexidine gluconate in 70% isopropyl alcohol is effective in 30 seconds.

233 Baseline 30 Seconds 10 Minutes 6 Hours FIGURE. Decrease in colony-forming units (CFU) after application of 2% chlorhexidine gluconate in 70% isopropyl alcohol on the abdomen. Humphries T. The establishment and validation of the mobile immunization team concept at a clinic level. workers: vectors of influenza virus? Low vaccination rate among hospital health care workers. To the Editor: A randomized, blinded clinical trial was conducted to determine the immediate and persistent antimicro-bial activity of 2% chlorhexidine glu-conate in 70% isopropyl alcohol the inclusion and exclusion criteria who were between 18 and 70 years of age with no evidence of dermatoses, dermatitis, inflammation, or injuries to the drug-application sites on the abdomen were eligible for the study. They were included if they had 2.2 logjQ or more colony-forming units (CFU) of bacteria per square centimeter of skin on the abdomen when they were screened and at baseline (zero time). The trial was divided into pretest, screening, and test periods. In the 14-day pretest period of the study, subjects were required to avoid the use of medicated soaps, lotions, shampoos, and deodorants, as well as skin contact with solvents, acids, and bases. Subjects also avoided using ultraviolet tanning beds or bathing in antimicrobial-treated pools or hot tubs. They were given personal hygiene kits that contained no antimicrobial ingredients. Subjects were not allowed to shave the treatment areas for 5 days before sampling or to bathe for 24 hours before microbial samples were taken. The screening period consisted of the week following the 14-day pretest period. The week following the screening period was the test period of the study. On test day 1, the subjects were scored for irritation and sampled for baseline microbial counts randomly on the right or left abdomen and groin using a cylinder sampling technique. 1 If the treatment area passed the screening test, a single dose of CHG+IPA was applied for 30 seconds to a 42-cm 2 area on the right or left abdomen and allowed to dry for 30 seconds. All of the sampling sites were scored for irritation before any microbial samples were taken. All sampling sites were randomized within treatment areas on the abdomen using a computer-generated random-ization schedule. Treatment areas were sampled for bacteria on the abdomen 30 seconds and 10 minutes after CHG+IPA application. After the 10-minute sample was taken, all treatment areas were covered with a gauze and fenestration bandage (Tegaderm, …